BACH1 and leukemia: For example, miR-155 modulates the expression of NF-κB and MAFK via regulation of BACH1 (BTB and CNC homology 1, basic leucine zipper transcription factor 1) and LDOC1 (leucine zipper, downregulated in cancer 1) which is critical to malignant transformation in leukemia, breast and lung cells (51–53).