The AKT1 (49.53 ± 1.965 vs. 34.40 ± 2.358, p < 0.01), GTSE1 (45.23 ± 2.045 vs. 37.33 ± 2.182, p = 0.01), BIRC5 (47.85 ± 2.197 vs. 27.80 ± 2.003, p < 0.01), AURKA (49.95 ± 2.408 vs. 34.40 ± 2.603, p < 0.01) and KNSTRN (43.79 ± 2.357 vs. 30.07 ± 2.039, p < 0.01) shows significantly higher expression in endometrial cancer than cancer adjacent tissue. The gene discussed is KNSTRN; the disease is cancer.