In addition, Beclin1 (BECN1), which is a key regulator of macroautophagy/autophagy and is involved in the production of the phosphatidylinositol 3-kinase (PtdIns3K) complex, was recently found to be a new driver of ferroptosis in a study showing that BECN1 may promote ferroptosis by regulating the activity of system xc- in cancer cells [39]. Here, BECN1 is linked to cancer.