ACTA1 and asthma: Besides, IF staining using α-SMA (airway remodeling marker) further confirmed that the expression and description of α-SMA in airway smooth muscle were robustly enhanced in asthma model group and Tetrandrine-treated group, while OVA-mediated increase of α-SMA was observably decreased in the condition of Tetrandrine, implying that Tetrandrine might reverse OVA-induced airway remodeling (Figure 1(c)).