It has been suggested that a significant increase of SIRT1 expression in hepatocellular carcinoma [23]; breast, prostate, ovarian, gastric, and colon cancers [25, 26, 28, 49, 50]; glioblastoma [51]; and lymphoma [52] might be associated with the development and invasion of tumors. The gene discussed is SIRT1; the disease is malignant colon neoplasm.