In a study by Vannucchi et al., which included 820 BCR-/ABL1-negative MPN patients in a period from 1980 to 2008, 11 concomitant LPD cases were reported, with a 3.44-fold increase in the risk of developing LPD in the MPN group compared with the general population [4]. This evidence concerns the gene BCR and myeloproliferative neoplasm.