The mammalian target of rapamycin (mTOR) signaling has been reported to be associated with regulation of microRNAs (miRNAs) which are involved in diverse processes such as lipid metabolism and play fundamental roles in maintaining endothelial homeostasis and controlling leukocyte trafficking and inflammation, affecting the development of atherosclerosis (Novak et al., 2015; Fernandez-Hernando and Suarez, 2018). This evidence concerns the gene MTOR and atherosclerosis.