As shown in Table 4, compared with the PP genotype subgroup, the L allele carriers (PL+LL genotype) of the GPx1 P198L polymorphism had significantly lower acne grade score (P = 0.004) and tended to have increased waist circumference, average ovarian volume, and MDA levels (P < 0.07) in the patients with PCOS. Here, GPX1 is linked to acne.