In a model of experimental atherosclerosis in hyperlipidemic ApoE-deficient mice treatment with the BD2 inhibitor apabetalone reduced the aortic lesion formation, decreased circulating adhesion molecules (haptoglobin, VCAM-1, IL-18, SAP, and M1P1a) and reduced mRNA levels of proinflammatory cytokines (IL-6 and VCAM1) in carotid tissue (Jahagirdar et al., 2014). Here, VCAM1 is linked to atherosclerosis.