The Western DP on the other hand, characterized by a high intake of red meats, fat dairy products, refined grains and sugars, has been positively correlated with higher concentrations of markers of endothelial dysfunction, the first step in CVD: fasting insulin, C peptide, leptin, C reactive protein, homocysteine, tissue plasminogen activator antigen, interleukin 6 (IL-6), E-selectin, intercellular adhesion molecule 1 (sICAM-1) and vascular cells of molecular adhesion 1 (sVCAM-1) (Defagó et al., 2014; Rodríguez-Monforte et al., 2015; Marchiori et al., 2017). The gene discussed is IL6; the disease is endothelial dysfunction.