Colitis models treated with DPA-derived maresin 1 by Marcon et al. [79] had also been demonstrated with significantly decreased levels of inflammatory cytokines, including IL-1β, IL-6, IFN-γ, and TNF-α in DSS-induced colitis protocol, as well as IL-1β and IL-6 in the TNBS-induced colitis protocol. This evidence concerns the gene TNF and colitis.