A characteristic of DSS-induced colitis is the momentous infiltrates in the inflammatory lesions, composing mainly of T and B lymphocytes, macrophages, and neutrophils that produce a variety of proinflammatory cytokines such as TNF-α, IL-6, IL-8, IL-12, IL-17, and IFN-γ [62, 70]. The gene discussed is IL17A; the disease is colitis.