Similarly, this analysis identified significant DMRs overlapping genes coding for or related to retinoid X receptors (RXRB, ITGB3BP), genes integral to adult neurogenesis and synaptic development and positioning (e.g., AKT2, SYNGAP1, FOXG1, CTNND2, MEF2C, and AIMP1), risk for schizophrenia (e.g., CLSTN3, FARSB, MYOM2, SOX2-OT, SLC39A7, SDCCAG8, and LRRC36), immune response (LRR1, FAM19A2, CMKLR1, and MMP2), and ion-gated channels and binding (e.g., SLC6A4, SLC6A12, SLC39A7, KCNJ5, CLSTN3, and PLS3). The gene discussed is CLSTN3; the disease is schizophrenia.