In univariate analysis, the factors related to poor prognoses included location of intestinal ulcers (ileocecal and colorectum), size of intestinal ulcers (> 1 cm), abnormal blood parameters (WBC > 6.4 × 109/L, Hb < 123 g/L, ESR > 24 mm/h, CRP > 44 mg/L), and poor compliance. The gene discussed is GSTM1; the disease is intestinal disorder.