In CANTOS, over 10,000 post-myocardial infarction patients with residual inflammatory risk (defined as high-sensitivity C-reactive protein (hs-CRP) concentrations ≥ 2 mg/L) and treated with currently mandated concomitant cardiovascular (CV) therapy randomly received placebo or one of 3 doses of the interleukin (IL)-1β neutralizing antibody canakinumab. This evidence concerns the gene CRP and myocardial infarction.