Vaspin belongs to family of newly discovered adipokines besides others such as retinol-binding protein 4 (RBP4), dipeptidyl peptidase 4 (DPP-4), bone morphogenetic protein (BMP)-4, BMP-7, and progranulin, recently implicated in various aspects of obesity [156]. This evidence concerns the gene DPP4 and obesity due to melanocortin 4 receptor deficiency.