Predicated on numerous complete responses in leukemia and lymphoma patients achieved via a single infusion of genetically engineered CAR-T cells, official approval was recently issued by the food and drug administration (FDA) as well as by the European medicines agency (EMA) for the use of CD19-CAR-T cells in acute lymphoblastic leukemia (ALL) and diffuse large cell B-cell lymphoma (DLBCL) [4]. The gene discussed is CD19; the disease is acute lymphoblastic leukemia.