CRP and synovitis: Only factors with P values below 0.1 in univariate logistic regression were further analyzed by multivariate logistic regression analysis (Table 5), which showed that the number of joints with synovitis on US at baseline (P=0.010, OR=1.438, 95%CI: 1.091–1.897) and CRP (P=0.047, OR=1.050, 95%CI: 1.001–1.102) were independent predictive factors for higher ACRpedi 50 response, while systemic JIA subtype (P=0.033, OR=0.152, 95%CI: 0.027–0.856) was an independent predictive factor for lower ACRpedi 50 response.