The challenges of accessing NAT for HCV RNA confirmation has been raised as a key barrier to improving diagnosis in resource‐limited settings in sub‐Saharan Africa and more specifically in the PWID population in Tanzania.13, 19, 22, 23 In this study we report the excellent performance of the Xpert® HCV VL Fingerstick assay to confirm viraemic HCV infection. The gene discussed is BRD2; the disease is infection.