For example, activated Stat3 can bond to DNA, access into the nucleus and stimulate the transcription of various genes that regulate important function of cells, including maintenance of cell survival, uncontrolled cellular proliferation, promotion of angiogenesis and facilitation of resistance to apoptosis induced by conventional chemotherapy.7 A recent study showed that infiltrating macrophages significantly enhanced Stat3 activation in drug‐resistant recurrent ovarian tumours compared to matched primary tumours. The gene discussed is STAT3; the disease is neoplasm.