MT-ATP6 and hydrops fetalis: Western blot assay showed that the expression of COX1 and ATPase6 proteins was both down-regulated of OBH-HF (P < 0.01 or P < 0.05) than those of WKY-ND, while HQQR treatment for 10 weeks could markedly increase the expression of COX1 and ATPase6 (P < 0.01) (Figure 3C,D).