PPARGC1A and hydrops fetalis: We found that the acetylation of PGC-1α was markedly increased in OBH-HF than that of WKY-ND (P < 0.05), which also showed a upward trend compared with SHR-ND, and HQQR treatment for 10 weeks could eliminate the change (P < 0.01) (Figure 4E,F).