Overexpression of JHDM1D-AS1 promoted the growth of tumor cells both in vivo and in vitro, which was mainly related to the increased expression of some tumor-derived angiogenic factors such as human hepatocyte growth factor (hHGF), human fibroblast growth factor 1 (hFGF1), and several inflammatory response genes, including mouse matrix metalloproteinase3 (mMmp3), mouse matrix metalloproteinase9 (mMmp9), mouse S100A8 protein (mS100a8), and mouse S100A9 protein (mS100a9) 47. This evidence concerns the gene HGF and neoplasm.