However, the results of these studies vary: some studies have shown that expression of PD-L1 was correlated with poor clinical outcomes in NSCLC26, 27; while others showed a favorable prognosis for NSCLC with PD-L1 expression28, 29.In our study, however, no significant correlations between PD-L1 protein expression and prognosis were found, when we analyzed the survival in strata of histology, still no association was found between PD-L1 protein expression and DFS or OS (data not shown). This evidence concerns the gene CD274 and non-small cell lung carcinoma.