And further Kaplan-Meier plotter prognostic analysis displayed that overexpression of the major FA anabolic enzymes (FASN, ACC, and SCD) were correlated to poor OS, while overexpression of the FA catabolic enzymes (CPT1A, HADHA, HADHB, and ACAT1) were correlated to favorable OS in ccRCC patients (P<0.05). The gene discussed is HADHB; the disease is nonpapillary renal cell carcinoma.