To identify the dysregulated EMT-related genes in NPM1-mutated AML, we firstly determined the differentially expressed genes (DEGs) between AML with or without NPM1 mutation using three publicly available datasets: the GSE34860 dataset (n = 79), the Cancer Genome Atlas (TCGA) dataset (n = 179), and the GSE6891 dataset (n = 461). Here, NPM1 is linked to acute myeloid leukemia.