In addition, We performed Ki67 and p-NF-κB assay of xenograft tumor tissues to measure proliferation and NF-κB activity of A549 cells in the xenograft tumor, the results showed in Fig. 7G-J suggested that combination treatment with BAY11-7082 increased the efficacy of EGCG in proliferation (brown color spots number of Ki67 decreased) and NF-κB activity inhibition (brown color spots number of P-NF-κB decreased) to some extent. This evidence concerns the gene MKI67 and neoplasm.