When the LOX inhibition group was compared with the control group, the enzyme activity of the active form of MMP-2 (62 kDa) in mouse tumor tissues was significantly decreased (Table 1, Fig. 2E, 2F) (P < 0.05) and the enzyme activity of the active form of MMP-9 (92 kDa) was significantly decreased (Table 1, Fig. 2E, 2G) (P < 0.05). The gene discussed is LOX; the disease is neoplasm.