Moreover, the infant bilirubin load is further increased by increased enterohepatic circulation of bilirubin.16 Although the UGT enzyme levels were not measured in the newborns in this study, the positive effects of glucocorticoids on liver development would result in increased UGT enzyme activation.17 Increased UGT activation is likely to result in increased bilirubin metabolism and a decrease in neonatal hyperbilirubinemia. This evidence concerns the gene SLC35A2 and Hyperbilirubinemia.