NOX1 and intestinal neoplasm: We demonstrated that oxidant-related triglycerides and oxidized phosphatidylcholines, such as aldehyde and carboxylic acid types, were increased in the serum of Min mice.(24) Moreover, we showed that NADPH oxidase 1 (NOX1) and p22phox mRNA levels tend to be elevated in the intestinal tumors of Min mice.(25) NOX1 and p22phox belong to a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase family that produces ROS.