•Griscelli syndrome: autosomal recessive mutation in myosin, together with its receptors and ligands; melanocytes do not transfer melanosomes to dendrites and peripheral keratinocytes, leading to attenuation of skin and hair color; presents with hypopigmentation, silvery-gray hair, immunodeficiency, reduced visual acuity with abnormal ocular movements, pancytopenia, hemophagocytic syndrome, and cerebral demyelination.118. This evidence concerns the gene MYH14 and immune system disorder.