TYR and albinism: Mutations in the TYR, OCA2, TYRP1, and SLC45A2 genes are the main cause of oculocutaneous albinism.2, 5, 10 Recently, another two new genes, SLC24A5 and C10orf11,20 have been identified as responsible for causing OCA6 and OCA7, respectively, giving a total of seven different types of albinism.