CYP46A1 and glioblastoma: Although there is a general down‐regulation of CYP46A1 in GBM compared with normal brain, higher expression of CYP46A1 was also observed in the Neural GBM molecular subtype (Fig 1G), which is associated with a more favourable prognosis, relative to the other subtypes based on the TCGA Verhaak‐2010 molecular classification of GBM (Noushmehr et al, 2010).