HPS3 and pericardial effusion: Knockdown of HPS1 (HPS1KDi6e7, HPS1KD ATG) and -5 (HPS5KD e12i12, HPS5KD ATG) results in a severe renal phenotype with pericardial effusion, yolk sac edema and protein loss, while HPS3 (HPS3KDe7i7, HPS3KD ATG) and -4 (HPS4KD e8i8, HPS4 KD ATG) induces, if present at all, only mild pericardial effusion, yolk sac edema and no protein loss in zebrafish larvae