ACTA2 and Hepatic fibrosis: On the contrary, ecKOm/m LSECs expressed lower levels of Col1a2 (encoding Collagen type I) and Acta2 (encoding α-SMA), two prominent mesenchymal markers, compared to WT LSECs, suggesting that MKL1 deficiency in endothelial may alleviate EndMT in the context of liver fibrosis in vivo.