Previous studies have shown that the risk of ovarian cancer in the general population is 1–2%, while the risk of population with BRCA1 mutant and BRCA2 mutant are 39–63% and 16.5–27%, respectively [18].BRCA mutant are closely associated with breast cancer and may be also related to prostate cancer [19], pancreatic cancer [20], and cutaneous melanoma [21]. Here, BRCA2 is linked to familial pancreatic carcinoma.