Additional baseline blood DMRs were close to TENM3, involved in neurite growth [29], SYMPK, involved in polyadenylation regulation of gene expression and which showed increased expression in AD [30], SLC44A4, associated with type 1 diabetes mellitus and human aging [31], ZMAT2, which had decreased expression in AD [32], ULK1, which may play a role in the autophagic degradation of amyloid beta (Aβ) [33], and RUNX2, which links bone health and cognitive function and anxiety-like behavior [34]. Here, RUNX2 is linked to Alzheimer disease.