Today, aberrant expression of all three TAM receptors has been documented in a vast number of cancers (reviewed in [42]), stimulating MEK/ERK, PI3K/AKT, JAK/STAT, p38, NFκB and FAK/RAC downstream pathways that provide tumor cells with enhanced proliferative, survival, migratory, invasive and chemo-resistant properties [42, 51, 52]. Here, AKT1 is linked to cancer.