KLK3 and prostate carcinoma: In Brazil, in supplementary health, routine medical appointments are usually made directly with a urologist, and in the SUS, routine consultations for prostate cancer screening are carried out by GPs, geriatricians or urologists and the recommendation of the Brazilian Society of Urology is that men should seek a urologist once a year for annual screening with DRE and PSA beginig with 50 years or 45 years for afro-descendents or men with family history of prostate cancer [7].