The GPR55 antagonist CID 16020046 (1, 2.5, 5 μM), CBD (1, 2.5 μM), a putative GPR55 antagonist and GPR55 small interfering RNA (siRNA) were used to block GPR55 activity of HCT116 colon cancer cells [104]. This evidence concerns the gene GPR55 and malignant colon neoplasm.