Four patterns of responses were observed: genes that responded to diet or diabetes in only one condition (Slc2a1/Glut1 and Slc27a1/Fatp1); genes that responded to diet in one condition and to diabetes on both diets (Slc2a10/Glut10, Slc27a2/Fatp2 and Slc27a5/Fatp5); genes that responded to diet in both metabolic conditions but to diabetes only on breeder diet (Slc2a8/Glut8, Slc27a3/Fatp3 and Cpt1b); Slc2a9/Glut9 expression was significantly different between all 4 conditions. The gene discussed is SLC2A1; the disease is diabetes mellitus.