Given the high metastasis and mortality of bladder cancer, here we declared the involvement of KIF3A in the progression of bladder cancer with the aim to clarify the effects and underlying molecular mechanisms of KIF3A‐mediated cellular events in vitro and in vivo, providing insights into whether KIF3A could serve as a promising therapeutic target for the treatment of bladder cancer from bench to clinic. Here, KIF3A is linked to urinary bladder carcinoma.