Zhang et al examined the expression levels of SNHG15 in PC cells and found that SNHG15 was significantly increased in PC cell lines.88, 89 SNHG15 silencing reduced prostate cancer cell growth in vitro and in vivo.30 Besides, knockdown of SNHG15 inhibited the migratory and invasive abilities of PC cells.30 Interestingly, SNHG15 reversed the progress of EMT presenting as reduction of E‐cadherin and enrichment of N‐cadherin, highlighting the involvement of SNHG15 in EMT regulation. This evidence concerns the gene SNHG15 and pachyonychia congenita.