In a single SNP analysis, the BTLA rs2171513 G>A genotype frequencies were 62.83% (GG), 32.67% (GA) and 4.50% (AA) in EGJA patients and 63.70% (GG), 32.27% (GA) and 4.03% (AA) in the cancer-free controls. The gene discussed is BTLA; the disease is cancer.