Further stratification into COD subtype GC patients with histological PCC revealed significantly higher expression of the IGF1 protein than in the other subtypes, whereas no such significant elevation of NXPE2 expression was observed (Fig. 4c), suggesting IGF1 as a good indicator correlated with molecular as well as histological subtypes. The gene discussed is IGF1; the disease is adrenal gland pheochromocytoma.