Gonzalez et al. compared levels of blood antioxidants and the gut microbiota with serum malondialdehyde (MDA) and C reactive protein (CRP) levels in 21 subjects with nonactive SLE; in this study, the serum copper content was positively associated with CRP levels, and CRP was also positively associated with the proportion of Lentisphaerae, Proteobacteria, and Verrucomicrobia in feces. This evidence concerns the gene CRP and systemic lupus erythematosus.