In the ROC analysis, serum levels of Eotaxin-1 (pg/ml) and SAA (mg/l) presented the best discriminative capacity regarding binary ordered, composite IBD endoscopic disease activity (area under the receiver operating characteristics curve (AuROC) 0.75 (SE: 0.06, 95% CI: 0.62–0.87, P < 0.001) for both serum Eotaxin-1 and SAA levels) (Table 3). Here, CCL11 is linked to irritable bowel syndrome.