There was no significant difference in the distribution of the 8 SNPs (rs11536889, rs1927906, rs1927911, rs2149356, rs4986790, rs4986791, rs2737190, rs787384) of TLR4 between patients with none/mild chronic periodontitis (nmCP) and moderate/severe chronic periodontitis (msCP) in the study. This evidence concerns the gene TLR4 and periodontitis.