ANGPTL8 and carcinoma: Betatrophin, also called as angiopoietin-like protein 8 (e.g., ANGPTL8), hepatocellular carcinoma-associated protein TD26 and chromosome 19 open reading frame 80 (C19orf80), TD26, refeeding induced fat and liver (RIFL) protein, and lipasin, is a novel protein predominantly secreted in the liver and the adipose tissue.