Based on the finding that Gal-1 is increased in MGC-803 cells in the EMT model treated with TGF-β1, and that the TGF-β1-induced EMT model promoted typical tube-like structures in MGC-803 cells, we next determined whether overexpression of Gal-1 promoted the VM formation of GC cells by inducing EMT. The gene discussed is TGFB1; the disease is gastric cancer.