Starenki D et al24 reported that mortalin was upregulated in human medullary thyroid carcinoma (MTC) tissues and its depletion robustly induces cell death and growth arrest by inducing transient extracellular signal-regulated kinase (MEK/ERK) activation and altering mitochondrial bioenergetics. This evidence concerns the gene HSPA9 and medullary thyroid gland carcinoma.