LGALS3 and atrial fibrillation: Pooled results with a random-effect model showed that baseline circulating Gal-3 levels were significantly higher in patients who developed AF recurrence compared to patients who did not develop AF recurrence after ablation (SMD: 0.74; 95% CI: 0.21 to 1.27; p = 0.007; Figure 2(a)) with considerable heterogeneity (p for Cochrane's Q test < 0.001; I2 = 89%).